Genetic Testing & Risk Assessment 

Know Your Chances

A risk factor is something that increases or decreases your chances of developing a disease such as cancer. But just because you have one or more risk factors does not mean you will be diagnosed with the disease. A woman may have ovarian cancer for no apparent reason, while another doesn’t have breast cancer even though her mother and other family members have been diagnosed with the disease.

So do you have a higher risk of breast and ovarian cancer? To estimate cancer risk you have to look at a number of factors. Here are some of the reasons why people may have different risk factors for developing breast or ovarian cancer compared with others.

  • Being a woman. Women are about 100 times more likely than men to develop breast cancer.
  • Being older. Approximately two-thirds of invasive breast cancers are diagnosed in women age 55 or older. Fifty percent of all ovarian cancers are diagnosed in women over the age of 63. Inheriting certain gene defects. Between 5-10% of breast cancer cases are linked to an inherited gene mutation called BRCA1 and BRCA2. The same genes also increase the chances of ovarian cancer.
  • Having a family history of the disease. A woman’s risk of breast cancer doubles if she has one first-degree relative with the disease and approximately triples with two first-degree relatives. Chances of ovarian cancer also get higher depending on the number of relatives with the disease.
  • Having a personal history of breast cancer. A woman who has had cancer in one breast has a three- to four-fold higher chance of developing a new cancer in either the other breast or another part of the same breast. She also may have an increased risk for ovarian cancer.
  • Being white. White women are more likely to develop breast cancer than black women.
  • Having dense breast tissue. These women who have more glandular tissue than fatty tissue have a higher risk of breast cancer.
  • Having certain benign breast conditions. Depending on the type of benign breast condition, a woman’s risk for breast cancer can increase one and a half to two times, up to four to five times higher than average.
  • Having more menstrual cycles. Women who started menstruating before age 12 or stopped after age 55 have an elevated breast cancer risk.
  • Giving birth. Women who have had children have a lower risk of both breast and ovarian cancer.
  • Being overweight. Overweight women have a higher chance of developing breast and ovarian cancer.
  • Undergoing gynecologic surgery. Having a tubal ligation decreases a woman’s chances of ovarian cancer by 67% and a hysterectomy by 33%.
  • Taking fertility drugs. The use of certain fertility drugs for longer than one year could increase the chance of developing ovarian tumors.

Women who are concerned about their risks for developing breast or ovarian cancer should talk with their doctor to learn more about the disease. For a free referral to an obstetrician/gynecologist in your area, call 866-724-6002.